Clinical Efficacy of Intramuscular Vaccinia Immune Globulin: A Literature Review
نویسندگان
چکیده
منابع مشابه
Clinical efficacy of intramuscular vaccinia immune globulin: a literature review.
BACKGROUND Numerous literature reports describe clinical efficacy of intramuscular vaccinia immune globulin (VIG) for complications of smallpox vaccination, prophylaxis of individuals with contraindications to vaccination, and prevention of smallpox among close contacts of patients with smallpox. METHODS We reviewed the literature regarding VIG treatment and prophylaxis of smallpox vaccine co...
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In 1980 the World Health Organization declared that smallpox was eradicated from the world, and routine smallpox vaccination was discontinued. Nevertheless, samples of the smallpox virus (variola virus) were retained for research purposes, not least because of fears that terrorist groups or rogue states might also have kept samples in order to develop a bioweapon. Variola virus represents an ef...
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Supplemental Figure Legends 182 Figure S1. Experimental design of VIG treatment using a murine model of EV. Mice 183 were EC sensitized with OVA or saline for 7 weeks followed by inoculation of 10 7 plaque 184 forming units/mouse by skin scarification. Mice were sacrificed after 7 days of VV inoculation 185 and examined for clinical responses, viral load, serum levels of VV antibodies and cytok...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2004
ISSN: 1058-4838,1537-6591
DOI: 10.1086/422999